Paediatric Influenza
Knowledge Transfer Series


An online environment designed to promote, educate and share information about the burden of seasonal influenza and its presence in Canada.

Clinical challenges in protecting children under 2 years of age from influenza

Accredited for 1.5 Mainpro+ credits

mdBriefCase eCME

Planning Committee

  • Brian Aw, MD, CCFP, CTH, ISTM
  • Ken Bayly, B.Sc., MD
  • Steve Black, MD
  • David Fisman, MD, MPH, FRCP(C)
  • Timo Vesikari, MD, PhD
  • Bruce Wheeler, MD, CCFP

Learning Objectives

  • Describe the burden of illness from influenza for children under 2 years of age
  • Identify and describe current and future influenza vaccine options for children under 2 years of age
  • Compare vaccine options with respect to efficacy, safety, and cost-effectiveness

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Video Resources

Influenza – flu virus mechanism

What is the mechanism behind the flu?

ICID Grand Rounds

Watch the experts discuss flu vaccines for little kids - What's new, what's true?

CIC Conference Footage

Watch the experts discuss new interventions for seasonal influenza - How to manage influenza in the elderly and pediatric population?

Physician Resources

Canadian Immunization Guide

Keep up with Canada's Immunization Guide. What are the most recent recommendations and statements provided by National Advisory Committee on Immunization (NACI) and the Committee to Advise on Tropical Medicine and Travel (CATMAT).

PHAC influenza facts

Debunk the myths! Here are some flu facts to help better undersand why the flu shot is so important.

Provincial and Territorial Immunization Information

What you need to know about influenza within your province.

Slide Decks

PCIRN presentation – Flu B

How does frailty relate to influenza?

ICID National Grand Rounds in Infectious Diseases

Flu Vaccines for Little Kids - What's new, What's True?

Managing Influenza in the Elderly and Paediatric Population

New Interventions for the prevention of seasonal influenza


Influenza Vaccine Responses in Older Adults

McElhaney, JE. 2010.


The most profound consequences of immune senescence with respect to public health are the increased susceptibility to influenza and loss of efficacy of the current split-virus influenza vaccines in older adults, which are otherwise very effective in younger populations. Influenza infection is associated with high rates of complicated illness including pneumonia, heart attacks and strokes in the 65+ population. Changes in both innate and adaptive immune function not only converge in the reduced response to vaccination and protection against influenza, but present significant challenges to new vaccine development. Read More

Prevention and Control of Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2015–16 Influenza Season

Centers for Disease Control and Prevention - Morbidity and Mortality Weekly Report - August 7, 2015.

Understanding the Challenges and Opportunities in Protecting Older Adults from Influenza, A Brief from the NFID

People of all ages can become infected with influenza virus, but the infection is particularly serious in older adults.

Immunosenescence: Influenza vaccination and the elderly.

Aging is associated with a decline in the normal function of the immune system, both cellular and humoral, which often leads to a state of 'immunosenescence'.

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